Publikationen

Schmitt C, Mauker P, Vepřek NA, Gierse C, Meiring JCM, Kuch J, Akhamanova A, Dehmelt L, Thorn-Seshold O.:
A Photocaged Microtubule-Stabilising Epothilone Allows Spatiotemporal Control of Cytoskeletal Dynamics.
Angew Chem Int Ed Engl, e202410169 (2024)

Nanda S, Calderon A, Sachan, A, Duong T-T, Koch J, Xin X, Solouk-Stahlberg D, Wu Y-W, Nalbant P, Dehmelt L:
Rho GTPase activity crosstalk mediated by Arhgef11 and Arhgef12 coordinates cell protrusion-retraction cycles.
Nat Commun, 14:8356 (2023) (corresponding author)

Patwardhan R, Nanda S, Wagner J, Stockter T,Dehmelt L, Nalbant P:
Cdc42 activity in the trailing edge is required for persistent directional migration of keratinocytes.
Mol Biol Cell, 35:br1 (2024) (corresponding author)

Nalbant P, Wagner J, Dehmelt L:
Direct investigation of cell contraction signal networks by light-based perturbation methods.
Pflugers Arch, 475:1439-1452 (2023) (corresponding author)

Kowalczyk M, Kamps D, Wu Y-W, Dehmelt L, Nalbant P:
Monitoring the response of multiple signal network components to acute chemo-optogenetic perturbations in living cells,
Chembiochem 23:e202100582 (2022) (corresponding author)

Kamps D, Koch J, Juma VO, Campillo-Funollet E, Graessl M, Banerjee S, Mazel T, Chen X, Wu Y-W, Portet S, Madzvamuse A, Nalbant P, Dehmelt L:
Optogenetic tuning reveals Rho amplification-dependent dynamics of a cell contraction signal network,
Cell Rep, 33:108467 (2020) (corresponding author)

Chen X, Venkatachalapathy M, Dehmelt L, Wu Y-W:
Multidirectional Activity Control of Cellular Processes by a Versatile Chemo-optogenetic Approach.
Angew Chem Int Ed, 57:11993 (2018)

Graessl M, Koch J, Calderon A, Kamps D, Banerjee S, Mazel T, Schulze N, Jungkurth JK, Patwardhan R, Solouk D, Hampe N, Hoffmann B, Dehmelt L, Nalbant P:
An excitable Rho GTPase signaling network generates dynamic subcellular contraction patterns,
J Cell Biol. 216:4271 (2017) (featured in Spotlight article J Cell Biol. 216: 3899; corresponding author)

Kamps D, Dehmelt L:
 Deblurring Signal Network Dynamics.
ACS Chem Biol. 12:2231 (2017) (corresponding author)

Chen X, Venkatachalapathy M, Kamps D, Weigel S, Kumar R, Orlich M, Garrecht R, Hirtz M, Niemeyer CM, Wu Y-W, Dehmelt L,
“Molecular Activity Painting”: Switch-like, Light-Controlled Perturbations inside Living Cells,
Angew Chem Int Ed 56:5916 (2017) (corresponding author)

Liu P, Calderon A, Konstantinidis G, Hou J, Voss S, Chen X, Li F, Banerjee S, Hoffmann J-E, Theiss C, Dehmelt L, Wu Y-W:
A bioorthogonal small-molecule-switch system for controlling protein function in live cells.
Angew Chem Int Ed 53:10049 (2014)

Mazel T, Biesemann A, Krejczy M, Nowald J, Müller O and Dehmelt L:
Direct observation of microtubule pushing by cortical dynein in living cells.
Mol Biol Cell 25:95 (2014) (corresponding author)

Arens J, Duong T-T and Dehmelt L:
A Morphometric Screen Identifies Specific Roles for Microtubule-Regulating Genes in Neuronal Development of P19 Stem Cells.
PLoS One8:e79796 (2013) (corresponding author)

Schönichen A, Mannherz HG, Behrmann E, Mazur AJ, Kühn S, Silván U, Schoenenberger C-A,Fackler OT, Raunser S, Dehmelt L and Geyer M:
FHOD1 is a combined actin filament capping and bundling factor that selectively associates with actin arcs and stress fibers.
J Cell Sci 126:1891 (2013)

Gandor S, Reisewitz S, Venkatachalapathy M, Arrabito G, Reibner M, Schröder H, Ruf K, Niemeyer CM, Bastiaens PIH, Dehmelt L:
A Protein Interaction Array Inside a Living Cell.
Angew Chem Int Ed 52:4790 (2013) (featured in Faculty of 1000 and Biotechniques 2013 55:11; corresponding author)

Blümer J, Rey J, Dehmelt L, Mazel T, Wu YW, Bastiaens P, Goody RS, Itzen A:
RabGEFs are a major determinant for specific Rab membrane targeting.
J Cell Biol 200:287 (2013) (featured in Faculty of 1000)

Milroy LG, Rizzo S, Calderon A, Ellinger B, Erdmann S, Mondry J, Verveer P, Bastiaens P, Waldmann H, Dehmelt L, Arndt HD:
Selective chemical imaging of static actin in live cells.
J Am Chem Soc 134:8480 (2012) (corresponding author)

Dehmelt L, Poplawski G, Hwang E, Halpain S:
NeuriteQuant: An open source toolkit for high content screens of neuronal morphogenesis.
BMC Neurosci 12:100 (2011) (corresponding author)

Dehmelt L:
The dynamics of the cellular skeleton. How molecular "speckles" can reveal cellular building blocks.
Systembiologie.De (Int. Ed.) 3:59 (2011) (corresponding author)

Dehmelt L and Bastiaens PI:
Spatial organization of intracellular communication: insights from imaging.
Nat Rev Mol Cell Biol 11:440 (2010)

Weinrich D, Köhn M, Jonkheijm P, Westerlind U, Dehmelt L, Engelkamp H, Christianen PC, Kuhlmann J, Maan JC, Nüsse D, Schröder H, Wacker R, Voges E, Breinbauer R, Kunz H, Niemeyer CM, Waldmann H.
Preparation of biomolecule microstructures and microarrays by thiol-ene photoimmobilization.
Chembiochem 11:235 (2010)

Dehmelt L, Nalbant P, Steffen W, Halpain S:
A Microtubule-Based, Dynein-Dependent Force Induces Local Cell Protrusions: Implications for Neurite Initiation.
Brain Cell Biology 35:39 (2006)

Dehmelt L, Smart FM, Ozer RS, Halpain S:
The role of microtubule-associated protein 2c in the reorganization of microtubules and lamellipodia during neurite initiation.
J Neurosci 23:9479 (2003)