Publications

Li L, Griebel ME, Uroz M, Bubli SY, Gagnon KA, Trappmann B, Baker BM, Eyckmans J, Chen CS (2024).
A protein-adsorbent hydrogel with tunable stiffness for tissue culture demonstrates matrix-dependent stiffness responses.
Adv Funct Mater 34(17):2309567.

Jain M, Trapani G, Trappmann B, Ravoo BJ (2024).
Stiffness modulation and pulsatile release in dual responsive hydrogels.
Angew Chem Int Ed, in press

Weiß MS, Trapani G, Long H, Trappmann B (2024)
Matrix resistance toward proteolytic cleavage controls contractility-dependent migration modes during angiogenic sprouting.
Adv Sci, in press.

Trapani G, Weiß MS, Trappmann B (2023).
Tunable synthetic hydrogels to study angiogenic sprouting.
Curr Protoc 3(8):e859.

Govindasamy N, Long H, Ranga A, Trappmann B, Bedzhov I (2023).
3D biomimetic environment enabling ex utero trophoblast invasion and co-culture of embryos and somatic cells.
STAR Protoc 4(3):102456.

Ozguldez HO, Govindasamy N, Fan R, Long H, Mildner K, Zeuschner D, Trappmann B, Ranga A, Bedzhov I (2023)
Polarity inversion reorganizes the stem cell compartment of the trophoblast lineage.
Cell Rep 42(4):112313.

Truszkowski L, Batur D, Long H, Tarbashevich K, Vos BE, Trappmann B, Raz E (2023).
Primordial germ cells adjust their protrusion type while migrating in different tissue contexts in vivo
Development 150(2):dev200603.

Trappmann, B (2022)
Cell scientist to watch
Journal of Cell Science Aug 2022 135 (16)

Long H, Vos BE, Betz T, Baker BM, Trappmann B (2022).
Nonswelling and Hydrolytically Stable Hydrogels Uncover Cellular Mechanosensing in 3D
Adv Sci 9:2105325.

Duong CN, Brückner R, Schmitt M, Nottebaum AF, Braun LJ, Meyer Zu Brickwedde M, Ipe U, Vom Bruch H, Schöler HR, Trapani G, Trappmann B, Ebrahimkutty MP, Huveneers S, de Rooij J, Ishiyama N, Ikura M, Vestweber D (2021).
Force-induced changes of ⍺-catenin conformation stabilize vascular junctions independently of vinculin.
J Cell Sci 134(24):jcs259012.

Govindasamy N, Long H, Jeong HW, Raman R, Özcifci B, Probst S, Arnold S, Riehemann K, Ranga A, Adams RH, Trappmann B^#, Bedzhov I^# (2021).
3D biomimetic platform reveals the first interactions of the embryo and the maternal blood vessels.
Dev Cell 56:3276-3287. ^#co-corresponding authors

Liu J, Long H, Zeuschner D, Räder AFB, Polacheck WJ, Kessler H, Sorokin L, Trappmann B (2021).
Synthetic extracellular matrices with tailored adhesiveness and degradability support lumen formation during angiogenic sprouting.
Nat Commun 12(1):3402.

Arif N, Holm M, Antu AN, Teber D, Grimlowski R, Schaefer K, Trappmann B, Grashoff C, Vestweber D (2021).
PECAM-1 supports leukocyte diapedesis by triggering tension-dependent dephosphorylation of VE-cadherin leading to its internalization.
EMBO J 40(9):106113

Yu L, Hou Y, Xie W, Camacho JLC, Cheng C, Holle A, Young J, Trappmann B, Zhao W, Melzig MF, Cavalcanti-Adam EA, Zhao C, Spatz JP, Wei Q, Haag R (2020)
Ligand Diffusion Enables Force-Independent Cell Adhesion via Activating a5b1 Integrin and Initiating Rac and RhoA Signaling.
Adv Mater 32(29):2002566.

Begemann I, Saha T, Lamparter L, Rathmann I, Grill D, Golbach L, Rasch C, Keller U, Trappmann B, Matis M, Gerke V, Klingauf J, Galic M (2019).
Mechanochemical self-organization determines search pattern in migratory cells.
Nat Phys 15:848-857.

Kato K, Dieguez-Hurtado R, Park DY, Hong SP, Kato-Azuma S, Adams S, Stehling M, Trappmann B, Wrana JL, Koh GY, Adams RH (2018).
Pulmonary pericytes regulate lung morphogenesis.
Nat Commun 9:2448.

Trappmann B*, Baker BM, Polacheck WJ, Choi CK, Burdick JA, Chen CS* (2017).
Matrix degradability controls multicellularity of 3D cell migration.
Nat Commun 8:371. *co-corresponding authors

Baker BM*, Trappmann B*, Wang WY, Sakar MS, Kim IL, Shenoy VB, Burdick JA, Chen CS. (2015).
Cell-mediated fibre recruitment drives extracellular matrix mechanosensing in engineered fibrillar microenvironments.
Nat Mater 14 (12):1262-8. *: equal contribution

Abhilash AS, Baker BM, Trappmann B, Chen, CS, Shenoy VB. (2014).
Remodeling of Fibrous Extracellular Matrices by Contractile Cells: Predictions from Discrete Fiber Network Simulations.
Biophys J 107(8):1829-40.

Blakely BL*, Dumelin CE*, Trappmann B*, McGregor LM, Choi CK, Anthony, PC, Duesterberg VK, Baker BM, Block SM, Liu DR, Chen CS. (2014).
A DNA-based molecular probe for optically reporting cellular traction forces.
Nat Methods 11(12):1229-32. *: equal contribution

Rodriguez NM, Desai RA, Trappmann B, Baker BM, Chen CS. (2014).
Micropatterned multicolour dynamically adhesive substrates to control cell adhesion and multicellular organization.
Langmuir 30(5):1327-1335.

Trappmann B, Chen CS. (2013)
How cells sense extracellular matrix stiffness: a material’s perspective.
Curr Opin Biotechnol 24(5): 948-53.

Baker BM, Trappmann B, Stapleton SC, Toro E, Chen CS. (2013).
Microfluidics embedded within extracellular matrix to define vascular architectures and pattern diffusive gradients.
Lab Chip 13(16):3246-52.

Trappmann B, Gautrot JE, Connelly JT, Strange DGT, Li Y, Oyen ML, Cohen Stuart MA, Boehm H, Li B, Vogel V, Spatz JP, Watt FM, Huck WTS. (2012).
Extracellular-matrix tethering regulates stem-cell fate.
Nat Mater 11(7):642-9.

Gautrot JE, Wang C, Liu X, Goldie SJ, Trappmann B, Huck WTS, Watt FM. (2012).
Mimicking normal tissue architecture and perturbation in cancer with engineered micro-epidermis.
Biomaterials 33(21):5221-9

Popeney CS, Setaro A, Mutihac RC, Bluemmel P, Trappmann B, Vonnemann J, Reich S, Haag R. (2012).
Polyglycerol-Derived Amphiphiles for the Solubilization of Single-Walled Carbon Nanotubes in Water: A Structure-Property Study.
Chemphyschem 13(1):203-11.

Bluemmel P, Setaro A, Popeney CS, Trappmann B, Haag R, Reich S. (2011).
Amphiphile replacement on carbon nanotube surfaces: Effect of aromatic groups on the interaction strength.
Phys Status Solidi B 248(11):2532-5.

Trappmann B*, Ludwig K*, Radowski MR, Shukla A, Mohr A, Rehage H, Böttcher C, Haag R. (2010)
A new family of nonionic dendritic amphiphiles displaying unexpected packing parameters in micellar assemblies.
J Am Chem Soc 132(32): 11119-24. *: equal contribution

Connelly JT, Gautrot JE, Trappmann B, Tan DW, Donati G, Huck WTS, Watt FM. (2010).
Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions.
Nat Cell Biol 12(7): 711-8.

Gautrot JE, Trappmann B, Oceguera-Yanez F, Connelly J, He X, Watt, FM, Huck WTS. (2010).
Exploiting the superior protein resistance of polymer brushes to control single cell adhesion and polarisation at the micron scale.
Biomaterials 31(18):5030-41.

Setaro A, Popeney CS, Trappmann B, Datsyuk V, Haag R, Reich S. (2010).
Polyglycerol-derived amphiphiles for single walled carbon nanotube suspension.
Chem Phys Lett 493(1-3):147-50.

Setaro A, Popeney CS, Trappmann B, Haag R, Reich S. (2010).
Interaction between single-walled carbon nanotubes and alkyl-polyglycerol derivatives.
Phys Status Solidi B 247(11-12):2758-61.

Azzaroni O, Trappmann B, van Rijn P, Zhou F, Kong B, Huck WTS. (2006).
Mechanically-induced generation of counterions inside surface-grafted charged macromolecular films: towards enhanced mechanotransduction in artificial systems.
Angew Chem Int Ed 45(44):7440-3