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Publications and Patents

ISI profile (query: Summerer D NOT Summerer, Drew)

PubMed profile

 

2024

*: Corresponding Author, §: Equally Contributed

91. B. Kosel, K. Bigler, B. C. Buchmuller, S. R. Acharyya, R. Linser*, and D. Summerer*
Evolved Readers of 5-Carboxylcytosine CpG Dyads Reveal a High Versatility of the Methyl-CpG-Binding Domain for Recognition of Noncanonical Epigenetic Marks
Angew. Chem. 2024, doi.org/10.1002/anie.202318837.

90. T. C. Lin, L. Engelhard, B. Söldner, R. Linser, and D. Summerer*
Light-Activatable MBD-Readers of 5-Methylcytosine Reveal Domain-Dependent Chromatin Association Kinetics In Vivo
Adv. Sci. 2024, 2307930, doi.org/10.1002/advs.202307930.

2023

89. Himanshu Singh, Chandan K. Das, Benjamin C. Buchmuller, Simone Eppmann, Lars V. Schäfer*, Daniel Summerer*, Rasmus Linser*
Epigenetic CpG Duplex Marks Probed by an Evolved DNA Reader via a Well-Tempered Conformational Plasticity
Nucleic Acids Res. 2023, 51(12), 6495-506, doi: 10.1093/nar/gkad134.

88. Jung, Anne; Muñoz López, Álvaro; Buchmuller, Benjamin; Banerjee, Sudakshina; Summerer, Daniel
Imaging-based in situ Analysis of 5-Methylcytosine at Low Repetitive Single Gene Loci with Transcription-Activator-Like Effector Probes
ACS Chem. Biol., 2023, 18(2), 230-36, doi: 10.1021/acschembio.2c00857

 

2022

87. S. Palei§, J. Weisner§, M. Vogt, R. Gontla, B. Buchmuller, C. Ehrt, T. Grabe, S. Kleinbölting, M. Müller, G. H. Clever*, Daniel Rauh,* and Daniel Summerer*
A high-throughput effector screen identifies a novel small molecule scaffold for inhibition of ten-eleven translocation dioxygenase 2
RSC Med. Chem., 2022, 13, 1540-48. Corrigendum: RSC Medicinal Chemistry, 2024, 15, 753 - 754.

86. T. C. Lin, S. Palei and D. Summerer*
Optochemical Control of TET Dioxygenases Enables Kinetic Insights into the Domain-Dependent Interplay of TET1 and MBD1 while Ox-idizing and Reading 5-Methylcytosine
ACS Chem. Biol.2022, 17(7), 1844-1852, 10.1021/acschembio.2c00245

85. Benjamin C. Buchmuller, Jessica Dröden, Himanshu Singh, Shubhendu Palei, Malte Drescher, Rasmus Linser* and Daniel Summerer*
Evolved DNA Duplex Readers for Strand-Asymmetrically Modified 5-Hydroxymethylcytosine/5-Methylcytosine CpG Dyads
J. Am. Chem. Soc., 2022, 144, 2987-93, doi: 10.1021/jacs.1c10678.

2021

84. J. Wolffgramm, B. Buchmuller, S. Palei, Á. Muñoz-López, J. Kanne, P. Janning, M. R. Schweiger* and D. Summerer*
Light-Activation of DNA-Methyltransferases
Angew. Chem., 2021, 60(24), 13507-12, doi: 10.1002/anie.202103945

83. J. Kanne§, M. Hussong§, J. Isensee, A. Muñoz-López, J. Wolffgramm, F. Heß, C. Grimm, S. Bessonov, L. Meder, J. Wang, H. C. Reinhardt, M. Odenthal, T. Hucho, R. Büttner, D. Summerer and M. R. Schweiger*
Pericentromeric satellite III transcripts induce etoposide resistance
Cell Death & Disease, 2021, 12(6), 530, doi: 10.1038/s41419-021-03810-9

82. B. Buchmuller, A. Jung, A. Munoz-Lopez and D. Summerer*
Programmable Tools for the Targeted Analysis of Epigenetic DNA Modifications
Curr. Opin. Chem. Biol., 2021, 63, 1-10doi: 10.1016/j.cbpa.2021.01.002

81. B. Buchmuller, A. Munoz-Lopez, M. Giess and D. Summerer*
Design and application of DNA modification-specific transcription-activator-like effectors
Meth. Mol. Biol., 2021, 2198, 381-99, doi: 10.1007/978-1-0716-0876-0_29

80. A. Munoz-Lopez, A. Jung, B. Buchmuller, J. Wolffgramm, S. Maurer, A. Witte and D. Summerer*
Engineered TALE Repeats for Enhanced Imaging-based Analysis of Cellular 5-Methylcytosine
ChemBioChem, 2021, 22(4), 645-51, doi: 10.1002/cbic.202000563

2020

79. A. Witte, A. Munoz-Lopez, M. Metz, M. R. Schweiger, P. Janning and D. Summerer*
Encoded, Click-Reactive DNA-Binding Domains for Programmable Capture of Specific Chromatin Segments
Chem. Sci., 2020, 11, 46, 12506-11, doi: 10.1039/D0SC02707C

78. S. Palei, B. Buchmuller, J. Wolffgramm, A. Munoz-Lopez, S. Jung, P. Czodrowski, D. Summerer*
Light-Activatable TET-Dioxygenases Reveal Dynamics of 5-Methylcytosine Oxidation and Transcriptome Reorganization
J. Am. Chem. Soc., 2020, 142, 7289-94. doi.org/10.1021/jacs.0c01193

77. B. Buchmuller, B. Kosel, D. Summerer*
Complete Profiling of Methyl-CpG-Binding Domains for Combinations of Cytosine Modifications at CpG Dinucleotides Reveals Differential Read-out in Normal and Rett-Associated States
Sci. Rep., 2020, 10 (1), 4053, doi: 10.1038/s41598-020-61030-1

76. A. Munoz-Lopez, B. Buchmuller, J. Wolffgramm, A. Jung, M. Hussong, J. Kanne, M. R. Schweiger* and D. Summerer*
Designer Receptors for Nucleotide Resolution Analysis of Genomic 5-Methylcytosine by Cellular Imaging
Angew. Chem. Int. Ed., 2020, 59 (23), 8927-31.  doi.org/10.1002/anie.202001935

75. B. Buchmuller, D. Summerer
Method for determining 5-methylcytosine configurations in DNA
Patent Application, 2020, 19 220 082.2, filed by the TU Dort­mund.

74. P. Widder, J. Schuck, D. Summerer* and M. Drescher*
Combining site-directed spin labeling in vivo and in-cell EPR Distance Determination
Phys. Chem. Chem. Phys., 2020, 22, 4875-9, doi: 10.1039/c9cp05584c

2019

73. T. Braun, P. Widder, U. Osswald, L. Groß, L. Williams, M. J. Schmidt, I. Helmle, D. Summerer* and Malte Drescher*
Isoindoline-Based Nitroxides as Bioresistant Spin Labels for Protein Labeling via Cysteines and Alkyne bearing Noncanonical Amino Acids 
ChemBioChem2019, doi: 10.1002/cbic.201900537.

72. M. Giess, A. Munoz-Lopez, B. Buchmuller, G. Kubik and D. Summerer*
Programmable Protein-DNA Crosslinking for the Direct Capture and Quantification of 5-Formylcytosine
J. Am. Chem. Soc., 2019, 141, 9453-7, doi: 10.1021/jacs.9b01432

71. P. Widder, F. Berner, D. Summerer* and M. Drescher*
Double Nitroxide Labeling by Copper-Catalyzed Azide-Alkyne Cycloadditions with Noncanonical Amino Acids for EPR Spectroscopy
ACS Chem. Biol.2019,14(5), 839-44, doi: 10.1021/acschembio.8b01111

70. A. Kugele, T. Braun, P. Widder, L. Williams, M. J. Schmidt, D. Summerer*, M. Drescher*
Site-Directed spin labelling of proteins by Suzuki-Miyaura coupling via a genetically encoded aryliodide amino acid
Chem. Commun., 2019, 55(13), 1923-1926, doi: 10.1039/c8cc09325c

69. T. Braun, M. Drescher* and D. Summerer*
Expanding the genetic code for site-directed spin-labeling
Int. J. Mol. Sci. ., 2019, 9, 20(2), E373, doi: 10.3390/ijms20020373
(Special Issue on “Expanding and Reprogramming the Genetic Code”, edited by K. Sakamoto).

2018

68. S. Maurer, B. Buchmuller, C. Ehrt, J. Jasper, O. Koch and D. Summerer*
Overcoming conservation in TALE-DNA interactions: A minimal repeat scaffold enables selective rerognition of an oxidized 5-methylcytosine
Chem. Sci., 2018, 9, 7247-52, doi: 10.1039/c8sc01958d

67. M. Gieß, A. Witte, J. Jasper, O. Koch and D. Summerer*
Complete, programmable decoding of oxidized 5-methylcytosine nucleobases in DNA by chemoselective blockage of universal transcription-activator-like effector repeats
J. Am. Chem. Soc., 2018, 140, 5904-8, doi: 10.1021/jacs.8b02909

66. H. Neumann*, P. Neumann-Staubitz, A. Witte and D. Summerer*
Epigenetic chromatin modification by amber suppression technology
Curr. Opin. Chem. Biol.2018, 45, 1-9, doi: 10.1016/j.cbpa.2018.01.017

65. M. J. Schmidt, and D. Summerer*
Directed evolution of orthogonal pyrrolysyl-tRNA synthetases in Escherichia coli for the genetic encoding of noncanonical amino acids
Meth. Mol. Biol.2018, 1728, 97-111, doi: 10.1007/978-1-4939-7574-7_5

64. A. Munoz-Lopez and D. Summerer*
Recognition of oxidized 5-methylcytosine derivatives in DNA by natural and engineered protein scaffolds
Chem. Rec.2018, 18(1), 105-16, doi: 10.1002/tcr.201700088

63. P. Rathi, S. Maurer and D. Summerer*
Selective recognition of N4-methylcytosine in DNA by engineered transcription-activator-like effectors
Philos. Trans. R. Soc. Lond. B Biol. Sci.2018, 373, 1748, doi: 10.1098/rstb.2017.0078
(Special Issue on “‘Frontiers in Epigenetic Chemical Biology”).

2017

62. P. Rathi, A. Witte and D. Summerer*
Engineering DNA backbone interactions results in TALE scaffolds with enhanced 5-methylcytosine selectivity
Sci. Rep.2017, 7, 15067, doi: 10.1038/s41598-017-15361-1

61. S. Flade, J. Jasper, M. Giess, M. Juhasz, A. Dankers, G. Kubik, O. Koch*, E. Weinhold* and D. Summerer*
The N6-position of adenine is a blind spot for TAL-effectors that enables effective binding of methylated and fluorophore-labeled DNA
ACS Chem. Biol., 2017, 12 (7), 1719-25, doi: 10.1021/acschembio.7b00324

2016

60. S. Maurer, M. Giess, O. Koch and D. Summerer*
Interrogating key positions of size-reduced TALE-repeats reveals a programmable sensor of 5-carboxylcytosine
ACS Chem. Biol., 2016,11 (12), 3294-9, doi: 10.1021/acschembio.6b00627

59. Y. J. Lee, M. J. Schmidt, J. M. Tharp, A. Weber, J. Gao, M. L. Waters, D. Summerer* and W. R. Liu*
Genetically encoded fluorophenylalanines enable insights into the recognition of lysine trimethylation by an epigenetic reader
Chem. Commun., 2016, 52 (85), 12606-9, doi: 10.1039/c6cc05959g

58. P. Rathi, S. Maurer, G. Kubik and D. Summerer*
Isolation of human genomic DNA sequences with expanded nucleobase selectivity
J. Am. Chem. Soc., 2016,138, 9910-18, doi: 10.1021/jacs.6b04807

57. P. Roser, M. J. Schmidt, M. Drescher* and D. Summerer*
Site-directed spin labeling of proteins for distance measurements in vitro and in cells
Org. Biomol. Chem., 2016,14, 5468-76, doi: 10.1039/c6ob00473c

56.G. Kubik and D. Summerer*
TALEored epigenetics: A DNA-binding scaffold for programmable epigenome editing and analysis
ChemBioChem., 2016,17, 975-80, doi: 10.1002/cbic.201600072

55. D. Summerer*, M. Giess, S. Maurer, G. Kubik
Transcription activator-like effector (TALE)-based decoding of cytosine nucleobases by selective modification response
Patent application., 2016, filed by the University of Konstanz.

2015

54. M. J. Schmidt, A. Fedoseev, D. Bücker, J. Borbas, C. Peter, M. Drescher* and D. Summerer*
EPR Distance measurements in native proteins with genetically encoded spin labels
ACS Chem. Biol., 2015, 18, 2764-71, doi: 10.1021/acschembio.5b00512

53. D. Summerer*
N6-Methyladenine: A potential epigenetic mark in eukaryotic genomes
Angew. Chem. Int. Ed., 2015, 54, 10714-6, doi: 10.1002/anie.201504594

52. M. J. Schmidt, A. Fedoseev, D. Summerer* and M. Drescher*
Genetically encoded spin labels for in vitro and in-cell EPR studies of native proteins
Methods Enzymol., 2015, 563, 483-502, doi: 10.1016/bs.mie.2015.05.023

51. G. Kubik and D. Summerer*
Deciphering epigenetic cytosine modifications by direct molecular recognition
ACS Chem. Biol., 2015, 10, 1580-9, doi: 10.1021/acschembio.5b00158

50. G. Kubik, S. Batke and D. Summerer*
Programmable sensors of 5-hydroxymethylcytosine
J. Am. Chem. Soc., 2015, 137, 2-5, doi: 10.1021/ja506022t

49. G. Kubik and D. Summerer*
Achieving single nucleotide resolution of 5-methylcytosine detection with TALEs
ChemBioChem., 2015, 16, 228-31, doi: 10.1002/cbic.201402408

48. B. Klauser, C. Rehm, D. Summerer and J. S. Hartig
Engineering of ribozyme-based aminoglycoside switches of gene expression by in vivo genetic selection in Saccharomycesc erevisiae
Methods Enzymol., 2015, 550, 301-20, doi: 10.1016/bs.mie.2014.10.037

47. D. Summerer, M. J. Schmidt, M. Drescher
Genetically encoded spin label
Patent application, 2015, PCT/EP2015/050568, filed by the University of Konstanz

2014

46. M. Pott, M. J. Schmidt and D. Summerer*
Evolved sequence contexts for highly efficient amber suppression with noncanonical amino acids
ACS Chem. Biol., 2014, 9, 2815-22, doi: 10.1021/cb5006273

45. G. Kubik, M. J. Schmidt, J. E. Penner and D. Summerer*
Programmable and highly resolved in vitro detection of genomic 5-methylcytosine by TALEs
Angew. Chem. Int. Ed., 2014, 53, 6002-6, doi: 10.1002/anie.201400436

44. M. J. Schmidt, A. Weber, M. Pott, W. Welte and D. Summerer*
Structural basis of furan-amino acid recognition by a polyspecific aminoacyl-tRNA-synthetase and its genetic encoding in human cells
ChemBioChem, 2014, 15, 1755-60, doi: 10.1002/cbic.201402006

43. M. J. Schmidt and D. Summerer*
Genetic code expansion as a tool to study regulatory processes of transcription
Front. Chem., 2014, 2 (7), 1-11, doi: 10.3389/fchem.2014.00007

42. M. J. Schmidt, J. Borbas, M. Drescher* and D. Summerer*
A genetically encoded spin label for electron paramagnetic resonance distance measurements
J. Am. Chem. Soc., 2014, 136, 1238-41, doi: 10.1021/ja411535q
Three times highlighted by Faculty of 1000 (including rating: “exceptional”)

41. D. Summerer, M. J. Schmidt
Intercalating amino acids
Patent application, 2014, PCT/EP2014/065601, filed by the University of Konstanz

40. D. Summerer, G. Kubik, M. J. Schmidt
Direct, programmable detection of epigenetic cytosine modifications using TAL effectors
Patent application, 2014, PCT/EP2014/001753, filed by the University of Konstanz

2013

39. M. J. Schmidt, D. Summerer*
Red-light-controlled protein-RNA crosslinking with a genetically encoded furan
Angew. Chem. Int. Ed., 2013, 52, 4690-93, doi: 10.1002/anie.201300754

2012

38. M. J. Schmidt, D. Summerer*
A need for speed: genetic encoding of rapid cycloaddition chemistries for protein labelling in living cells
ChemBioChem, 2012, 13, 1553-57, doi: 10.1002/cbic.201200321

PI, Biotech Industry (Epigenetics, Genomics/Transcriptomics)

37. D. Summerer*
High-throughput DNA sequencing beyond the four-letter code: epigenetic modifications revealed by single molecule bypass kinetics
ChemBioChem, 2010, 11, 2499-501, doi: 10.1002/cbic.201000569

36. D. Summerer*, D. Hevroni, A. Jain, O. Scheck, J. Parker, A. Caruso, P.F. Stähler, C.F. Stähler and M. Beier
A flexible and fully integrated system for amplification, detection and genotyping of genomic DNA targets based on microfluidic oligonucleotide arrays
N. Biotechnology, 2010, 27, 149-55, doi: 10.1016/j.nbt.2010.03.005

35. M. Beier, P. F. Stähler, C.F. Stähler, J. Leonhard, D. Summerer, S. Bau
Process for the investigation of nucleic acid populations
Patent application, 2010, DE102008061772A1, filed by febit holding gmbh

34. D. Summerer*, N. Schracke, H. Wu, Y. Cheng, S. Bau, C.F. Stähler, P.F. Stähler and M. Beier
Targeted high throughput sequencing of a cancer-related exome subset by specific sequence capture with a fully automated microarray platform
Genomics, 2010, 95, 241-6, doi: 10.1016/j.ygeno.2010.01.006

33. C.F. Stähler, P.F. Stähler, M. Beier, D. Summerer
Integrated amplification, processing and analysis of biomolecules in a microfluidic reaction medium
Patent application, 2010, WO2010043418, filed by febit holding gmbh

32. D. Summerer*
Enabling technologies of genomic-scale sequence enrichment for high throughput sequencing
Genomics, 2009, 94, 363-8, doi: 10.1016/j.ygeno.2009.08.012

31. N. Schracke, M. Kränzle, P. F. Stähler, D. Summerer and M. Beier
Specific sequence selection and next generation resequencing of 68 E. coli genes using HybSelect
N. Biotechnology, 2009, 26, 229-33, doi: 10.1016/j.nbt.2009.08.013

30. D. Summerer*, H. Wu, B. Haase, Y. Cheng, N. Schracke, C.F. Stähler, M.S. Chee, P.F. Stähler and M. Beier
Microarray-based multicycle-enrichment of genomic subsets for targeted next-generation sequencing
Genome Res., 2009, 19, 1616-21, doi: 10.1101/gr.091942.109
Described methodology was highlighted in the Faculty of 1000s magazine The Scientist: “The ten most exciting tools to hit the life sciences in 2009″

29. S. Bau, N. Schracke, M. Kränzle, H. Wu, J. D. Hoheisel, P. F. Stähler, M. Beier and D. Summerer*
Targeted next-generation-sequencing by specific capture of multiple genomic loci using microfluidic low-volume DNA arrays
Anal. Bioanal. Chem., 2009, 393, 171-5, doi: 10.1007/s00216-008-2460-7

28. C.F. Stähler, P.F. Stähler, M. Beier, S. Bau, D. Summerer
Flexible extraction method for the production of sequence-specific molecule libraries
Patent application, 2009, WO2009065620, filed by febit holding gmbh

27. C.F. Stähler, P.F. Stähler, M. Beier, D. Summerer, M. Matzas, S. Vorwerk
Improved molecular biological processing system
Patent application, 2008, WO2008080629, filed by febit holding gmbh

Postdoc, The Scripps Research Institute (Chemical Biology, Genetic Code Expansion)

26. D.H. Jones, S.E. Cellitti, X. Hao, Q. Zhang, M. Jahnz, D. Summerer, P.G. Schultz, T. Uno, B.H. Geierstanger
Site-specific labeling of proteins with NMR-active unnatural amino acids
J. Biomol. NMR, 2010, 46, 89-100, doi: 10.1007/s10858-009-9365-4

25. E.M. Tippmann, W. Liu, D. Summerer, Mack A.V. and P.G. Schultz
A genetically encoded diazirine photocrosslinker in Escherichia Coli
ChemBioChem, 2007, 8, 2210-4, doi: 10.1002/cbic.200700460

24. E.A. Lemke§, D. Summerer§, B.H. Geierstanger, S.M. Brittain and P.G. Schultz
Control of protein phosphorylation with a genetically encoded photocaged amino acid
Nature Chem. Biol., 2007, 3, 769-72, doi: 10.1038/nchembio.2007.44
Faculty of 1000 evaluation: factor 10, exceptional.
Highlighted in Analytical Chemistry, January 1, 2008, “Photocaged amino acids enable scientists to study phosphorylation in vivo“
Highlighted by Arnaud, CH, Chemical & Engineering News, 2007, October 31, “Modified Serine Controls Protein Phosphorylation”
Highlighted by Richards, NGJ, The HFSP Journal, 2008, 2(2), 57-60 “Shining a light on posttranslational modification”

23. D. Summerer, S. Chen, N. Wu, A. Deiters, J.W. Chin and P.G. Schultz
A genetically encoded, fluorescent amino acid
Proc. Nat. Acad. Sci. USA, 2006, 103, 9785-9, doi: 10.1073/pnas.0603965103
Faculty of 1000 evaluation: factor 8, must read

22. Peter G. Schultz, Alexander Deiters, Lital Alfonta, Jonathan R. Chittuluru, Dan Groff, Daniel Summerer, Meng-Lin Tsao, Jiangyun Wang, Ning Wu, Jianming Xie and Huaqiang Zeng
Orthogonal translation components for the in vivo incorporation of unnatural amino acids
Patent application, 2006, WO2006110182, filed by the Scripps Research Institute, licensed to Novartis.

21. M.L. Tsao, D. Summerer, P.G. Schultz
The genetic incorporation of a distance probe into proteins in Escherichia coli
J. Am. Chem. Soc., 2006, 128, 4572-3, doi: 10.1021/ja058262u

20. A. Deiters, T.A. Cropp, D. Summerer, M. Mukherji, P.G. Schultz
Site-specific PEGylation of proteins containing unnatural amino acids
Bioorg. Med. Chem. Lett. 2004, 14, 5743-5, doi: 10.1016/j.bmcl.2004.09.059

PhD, University of Bonn (Chemical Biology, DNA Replication)

19. D. Summerer*
DNA polymerase profiling
Meth. Mol. Biol., 2008, 225, doi: 10.1007/978-1-60327-040-3_16

18. D. Summerer, N.Z. Rudinger, I. Detmer, A. Marx
Enhanced fidelity of mismatch extension by DNA polymerase through directed combinatorial enzyme design
Angew. Chem. Int. Ed., 2005, 44, 4712-5, doi: 10.1002/anie.200500047

17. D. Summerer, A. Marx
4´-C-Ethynylthymidine acts as a chain terminator during DNA-synthesis catalyzed by HIV-1 reverse transcriptase
Bioorg. Med. Chem. Lett., 2005, 15, 869-71, doi: 10.1016/j.bmcl.2004.12.072

16. A. Marx, Nikolas Z. Rudinger, D. Summerer
Mutated DNA Polymerases with increased mispairing discrimination
Patent application, 2005, WO2005074350, filed by the University of Bonn, licensed to Qiagen.

15. A. Marx, D. Summerer
Bigger DNA: New genetic helix with expanded size
Angew. Chem. Int. Ed., 2004, 43, 1625-6, doi: 10.1002/anie.200301737

14. M. Strerath, J. Gaster, D. Summerer, A. Marx
Increased single-nucleotide discrimination of PCR by primer probes bearing hydrophobic 4’-C-modifications
ChemBioChem, 2004, 5, 333-9, doi: 10.1002/cbic.200300757

13. A. Marx, D. Summerer, M. Strerath
Selectivity of DNA replication
Highlights in Bioorganic Chemistry: Methods and Application, Editors: C. Schmuck, H. Wennemers, WILEY-VCH, 2004, 299-308

12. A. Marx, I. Detmer, J. Gaster, D. Summerer
Probing DNA polymerase function with synthetic tools
Synthesis, 2004, 1, 1-14, doi: 10.1055/s-2003-44363

11. D. Summerer and A. Marx
4′-C-Modified nucleotides as chemical tools for investigation and modulation of DNA polymerase function
Synlett, 2004, 2, 217-24

10. A. Marx, M. Strerath, D. Summerer, A. Pingoud, B. Tews, M. Hahn, P. Friedhoff, J. Wilhelm
Improved method for allele-specific PCR
Patent application, 2003, WO2003072814, filed by Roche Diagnostics gmbh / Hoffmann La Roche

9. B. Tews, J. Wilhelm, D. Summerer, M. Strerath, A. Marx, P. Friedhoff, A. Pingoud, M. Hahn
Application of the C4´-alkylated deoxyribose primer system (CAPS) in allele specific real-time PCR for increased selectivity in discrimination of single nucleotide sequence variants
Biol. Chem. 2003, 384, 1533-41, doi: 10.1515/BC.2003.170

8. I. Detmer, D. Summerer, A. Marx
Substrates for investigation of DNA polymerase function: Synthesis and properties of 4’-C-alkylated oligonucleotides
Eur. J. Org. Chem. 2003, 10, 1837-46, doi: 10.1002/ejoc.200200641

7. I. Detmer, D. Summerer, A. Marx
DNA minor groove hydration probed with 4’-alkylated thymidines
Chem. Commun. 2002, 20, 2314-5, doi: 10.1039/b207582m

6. D. Summerer, A. Marx
A molecular beacon for quantitative monitoring of the DNA polymerase reaction in real-time
Angew. Chem. Int. Ed. 2002, 41, 3620-2, doi: 10.1002/1521-3773(20021004)41:19<3620::AID-ANIE3620>3.0.CO;2-C

5. M. Strerath, D. Summerer, A. Marx
Varied DNA polymerase-substrate interactions in the nucleotide binding pocket
ChemBioChem 2002, 3, 578-80, doi: 10.1002/1439-7633(20020603)3:6<578::AID-CBIC578>3.0.CO;2-W

4. D. Summerer, A. Marx
Differential minor groove interactions between DNA polymerase and sugar backbone of primer and template strands
J. Am. Chem. Soc. 2002, 124, 910-1, doi: 10.1021/ja017244j

3. A. Marx, D. Summerer
Molecular insights into error-prone DNA replication and error-free lesion bypass
ChemBioChem 2002, 3, 405-8, doi: 10.1002/1439-7633(20020503)3:5<405::AID-CBIC405>3.0.CO;2-4
Highlighted by Faculty of 1000

2. D. Summerer, A. Marx
DNA-templated synthesis: More versatile than expected
Angew. Chem. Int. Ed. 2002, 41, 89-90, doi: 10.1002/1521-3773(20020104)41:1<89::AID-ANIE89>3.0.CO;2-G

1. D. Summerer, A. Marx
DNA polymerase selectivity: sugar interactions monitored with high fidelity nucleotides
Angew. Chem. Int. Ed. 2001, 40, 3693-5, doi: 10.1002/1521-3773(20011001)40:19<3693::aid-anie3693>3.0.co;2-o