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The Clever Lab is equipped with a range of techniques for multistep organic and inorganic synthesis, compound purification, structure elucidation and analysis of multiple properties. Besides the below listed machines, the Department of Chem­is­try and Chemical Biology at TU Dort­mund Uni­ver­sity, as well as its embedding in the Uni­ver­sity Alliance Ruhr, opens pos­si­bi­lities to access an even wider range of spectroscopies, microscopies and other methods such as EPR, time-resolved fs spectroscopy, TEM, AFM and many more in collaboration.

NMR spectrometer

500 MHz Bruker Avance neo NMR spectrometer © Ralf Maserski​/​TU Dort­mund

500 MHz Bruker Avance neo NMR spectrometer with different probe heads, temperature control unit and sample changer. A range of further NMR spectrometers up to 700 MHz is available in the de­part­ment.

Mass spectrometer

High-resolution Ion Mobility-ESI mass spectrometer Bruker timsTOF © Ralf Maserski​/​TU Dort­mund

High-resolution Ion Mobility-ESI mass spectrometer Bruker timsTOF with HPLC and syringe pump infusion, glove box connection and cold spray ionization (cryo ESI) source.

This machine is not only suited to obtain the mass/charge ratio of supramolecular analytes with high precision and isotopic pattern resolution, it also delivers a value for the gas phase ion mobility, which can be converted into a collisional cross section (CCS in Å2). CCS values are indicative of an ions size and shape and can be used to distinguish isomers (with same m/z), simplify the analysis of complex mixtures and obtain valuable in­for­mation about conformational flexibility and structural switching processes. We further use software tools to calculate theoretical CCS values from molecular models or X-ray structures in order to compare them with the experimental values.

The cryo-ESI source allows injection of analytes at much lower temperatures than usually applied in ESI sources, thus enabling the MS detection of very fragile coordination compounds or non-covalent adducts.


Single crystal X-ray diffractometer Bruker D8 Venture © Ralf Maserski​/​TU Dort­mund

Single crystal X-ray diffractometer (Bruker D8 Venture, with Incoatec Microsources 3.0 Cu and Mo, Photon II detector) for crystal structure elucidations of organic, inorganic, supramolecular and biopolymeric species.

In cases where microscopic crystal sizes, enormous units cells, highly disordered side chains and solvents lead to poor diffraction, we are fully equipped to freeze mounted crystals, kept in standardized pucks, contained in transportable dewars, down to liquid nitrogen temperature and bring them to synchrotron sources such as DESY’s Petra III, P11, beamline in Hamburg to collect diffraction data.

Glovebox and SPS

Glovebox, coupled to a solvent purification system (SPS) © Ralf Maserski​/​TU Dort­mund

Glovebox, coupled to a solvent purification system (SPS).

The argon-filled containment allows handling highly sensitive substrates, reaction intermediates and supramolecular species without risking exposure to oxygen and moisture. A selection of dry solvents can be withdrawn outside or directly from within the glovebox.

UV-Vis spectrometer

DAD HP-8453 UV-Vis

DAD HP-8453 UV-Vis Spectrometer © Ralf Maserski​/​TU Dort­mund

Spectrometer with kinetics software and adapter for Unisoku Coolspek temperature-con­trolled cuvette holder.

Jasco V-650 and Jasco V-750

Two temperature controlled UV-Vis spectrometers © Ralf Maserski​/​TU Dort­mund

Two temperature con­trolled UV-Vis spectrometers with 5x cuvette changer for DNA melting curve analysis.

Fluorescence spectrometer

Jasco FP-8300 fluorescence spectrometer © Ralf Maserski​/​TU Dort­mund

Jasco FP-8300 fluorescence spectrometer with adapter for Unisoku Coolspek temperature-con­trolled cuvette holder.

CD spectrometer

Circular Dichroism (CD) spectrometer © Ralf Maserski​/​TU Dort­mund

Circular Dichroism (CD) spectrometer (Applied Photophysics qCD Chirascan) with temperature-con­trolled cuvette holder.

Jasco CPL-300 CPL Spectrometer

Picture of the Jasco CPL-300 CPL Spectrometer and the attached computer. Please provide a copyright notice

Jasco CPL-300 CPL spectrometer with temperature-con­trolled cuvette holder. This instrument allows the determination of circularly polarized emission from chiral luminescent compounds and supramolecular aggregates.

Spectro-electrochemistry setup

Metrohm Autolab PGSTAT-101 © Ralf Maserski​/​TU Dort­mund

Metrohm Autolab PGSTAT-101 with Avantes light source and DAD UV-Vis spectrometer, various electrodes, reaction cells and cuvettes.


Malvern Microcal Peaq Isothermal Titration Calorimetry © Ralf Maserski​/​TU Dort­mund

Malvern Microcal Peaq Isothermal Titration Calorimetry (ITC) with Hastelloy cell, washing unit and different software tools for data interpretation.

Melting point apparatus

Melting point apparatus © Ralf Maserski​/​TU Dort­mund

Stuart SMP30


Normal Phase HPLC

Normal Phase HPLC © Ralf Maserski​/​TU Dort­mund

Agilent Technologies 1260 Infinity with autosampler, UV-Vis detector, fraction collector and various columns, in­clu­ding chiral ones for the se­pa­ra­tion of enantiomers

Two reversed phase HPLC systems

Two reversed phase HPLC systems © Ralf Maserski​/​TU Dort­mund

Agilent Technologies 1260 Infinity I/II with autosampler, DAD detector, column oven, for the analysis and purification of DNA strands.


Two preparative recycling gel permeation chromatography systems © Ralf Maserski​/​TU Dort­mund

Two preparative recycling gel permeation chromatography systems (GPC, from Japan Analytical Industry) with columns for different organic solvents. GPC purification is usually the last purification step for organic ligands before applying them in metal-mediated self-assembly.


MPLC cartridge purification system © Ralf Maserski​/​TU Dort­mund

Biotage Isolera One MPLC cartridge purification system with TLC simulating software and automated fraction collector.

Microwave reactor

Microwave reactor © Ralf Maserski​/​TU Dort­mund

CEM Discover SP for heating reaction mixtures in open and closed vessels


3D-Printer © Ralf Maserski​/​TU Dort­mund

Filament Deposition Modeling (FDM) 3D Printer (Ultimaker 3) with two printing heads for simultaneous extrusion of durable PLA (poly lactide) plastic for printing molecular models and X-ray structures and water-dissolvable PVA (poly vinyl alcohol) support meant to keep the PLA in place during printing.

DNA Synthesizer

DNA Synthesizer © Ralf Maserski​/​TU Dort­mund

K&A Laborgeraete H-8 for the simultaneous preparation of up to eight oligonucleotide strands by phosphoramidite solid phase synthesis.

Gel Documentation

Gel Documentation system © Ralf Maserski​/​TU Dort­mund

Gel Documentation system (Intas Gel IX 20).

Vacuum centrifuges

Vacuum centrifuges © Ralf Maserski​/​TU Dort­mund

Two vacuum centrifuges (H.Saur S-Concentrator BA-VC-300H)


Thermo Scientific Nanodrop One © Ralf Maserski​/​TU Dort­mund

Thermo Scientific Nanodrop One for elucidation of DNA concentration.

Glassware washer

Lab glassware washer © Ralf Maserski​/​TU Dort­mund

Lab glassware washer (Steelco lab 500 DRS)

Irradiation equipment

Irradiation equipment with 500W lamp © Ralf Maserski​/​TU Dort­mund

For photochemical conversions, consisting of a 500 W Hg lamp, different filters and power LED modules

Polarization microscope

Leica DM2500LED polarization microscope © Ralf Maserski​/​TU Dort­mund

Leica DM2500LED polarization microscope in­clu­ding camera and Linkam LTSE420 temperature stage for material characterization


Workstations for DFT calculations and MD simulations © Ralf Maserski​/​TU Dort­mund

Several Xeon multiprocessor workstations for DFT calculations and MD simulations

Location & approach

The campus of TU Dort­mund Uni­ver­sity is located close to interstate junction Dort­mund West, where the Sauerlandlinie A 45 (Frankfurt-Dort­mund) crosses the Ruhrschnellweg B 1 / A 40. The best interstate exit to take from A 45 is "Dort­mund-Eichlinghofen" (closer to Cam­pus Süd), and from B 1 / A 40 "Dort­mund-Dorstfeld" (closer to Cam­pus Nord). Signs for the uni­ver­si­ty are located at both exits. Also, there is a new exit before you pass over the B 1-bridge leading into Dort­mund.

To get from Cam­pus Nord to Cam­pus Süd by car, there is the connection via Vo­gel­pothsweg/Baroper Straße. We recommend you leave your car on one of the parking lots at Cam­pus Nord and use the H-Bahn (suspended monorail system), which conveniently connects the two campuses.

TU Dort­mund Uni­ver­sity has its own train station ("Dort­mund Uni­ver­si­tät"). From there, suburban trains (S-Bahn) leave for Dort­mund main station ("Dort­mund Hauptbahnhof") and Düsseldorf main station via the "Düsseldorf Airport Train Station" (take S-Bahn number 1, which leaves every 20 or 30 minutes). The uni­ver­si­ty is easily reached from Bo­chum, Essen, Mülheim an der Ruhr and Duis­burg.

You can also take the bus or subway train from Dort­mund city to the uni­ver­si­ty: From Dort­mund main station, you can take any train bound for the Station "Stadtgarten", usually lines U41, U45, U 47 and U49. At "Stadtgarten" you switch trains and get on line U42 towards "Hombruch". Look out for the Station "An der Palmweide". From the bus stop just across the road, busses bound for TU Dort­mund Uni­ver­sity leave every ten minutes (445, 447 and 462). Another option is to take the subway routes U41, U45, U47 and U49 from Dort­mund main station to the stop "Dort­mund Kampstraße". From there, take U43 or U44 to the stop "Dort­mund Wittener Straße". Switch to bus line 447 and get off at "Dort­mund Uni­ver­si­tät S".

The H-Bahn is one of the hallmarks of TU Dort­mund Uni­ver­sity. There are two stations on Cam­pus Nord. One ("Dort­mund Uni­ver­si­tät S") is directly located at the suburban train stop, which connects the uni­ver­si­ty directly with the city of Dort­mund and the rest of the Ruhr Area. Also from this station, there are connections to the "Technologiepark" and (via Cam­pus Süd) Eichlinghofen. The other station is located at the dining hall at Cam­pus Nord and offers a direct connection to Cam­pus Süd every five minutes.

The AirportExpress is a fast and convenient means of transport from Dort­mund Airport (DTM) to Dort­mund Central Station, taking you there in little more than 20 minutes. From Dort­mund Central Station, you can continue to the uni­ver­si­ty campus by interurban railway (S-Bahn). A larger range of in­ter­na­tio­nal flight connections is offered at Düsseldorf Airport (DUS), which is about 60 kilometres away and can be directly reached by S-Bahn from the uni­ver­si­ty station.

The facilities of TU Dort­mund Uni­ver­sity are spread over two campuses, the larger Cam­pus North and the smaller Cam­pus South. Additionally, some areas of the uni­ver­si­ty are located in the adjacent "Technologiepark".

Site Map of TU Dort­mund Uni­ver­sity (Second Page in English).