We mostly use biochemistry and molecular biology as tools to get access to the proteins of our interest. Our labs are generously equipped with excellent gadgets from basic bacterial expression up to eukaryotic hosts.
We do, however, have experience with the development of labeling schemes for NMR sample preparation via "non-standard" approaches.
One out of our two brand-new ÄKTA systems and part of our shaker racks.
Methyl-labeled cell-free expression for eukaryotic membrane proteins
R. Linser, V. Gelev, F. Hagn, S. G. Hyberts, H. Arthanari, G. Wagner,
“Selective methyl labeling of eukaryotic membrane proteins using cell-free expression”,
J. Am. Chem. Soc. 136 (32), 11308–11310 (2014),
Cover: J. Am. Chem. Soc., 2014, 136 (32), front page.
Spotlights article: J. Am. Chem. Soc., 2014, 136 (32), 11197.