Publications

Nanda S, Calderon A, Sachan A, Duong TT, Koch J, Xin X, Solouk-Stahlberg D, Wu YW, Nalbant P, Dehmelt L. (2023)
Rho GTPase activity crosstalk mediated by Arhgef11 and Arhgef12 coordinates cell protrusion-retraction cycles.
Nat Commun 14:8356

Patwardhan R, Nanda S, Wagner J, Stockter T, Dehmelt L, Nalbant P. (2024)
Cdc42 activity in the trailing edge is required for persistent directional migration of keratinocytes.
Mol Biol Cell. 35:br1

Nalbant P, Wagner J, Dehmelt L. (2023)
Direct investigation of cell contraction signal networks by light-based perturbation methods.
Pflugers Arch. 475:1439

Wiedemann B, Kamps D, Depta L, Weisner J, Cvetreznik J, Tomassi S, Gentz S, Hoffmann JE, Müller MP, Koch O, Dehmelt L, Rauh D.
Design and synthesis of Nrf2-derived hydrocarbon stapled peptides for the disruption of protein-DNA-interactions.
PLoS One. 17:e0267651

Pätzold F, Stamm N, Kamps D, Specht M, Bolduan P, Dehmelt L, Weberskirch R. (2022)
Synthesis and Characterization of Cationic Hydrogels from Thiolated Copolymers for Independent Manipulation of Mechanical and Chemical Properties of Cell Substrates.
Macromol Biosci. 22:e2100453

Kowalczyk M, Kamps D, Wu Y, Dehmelt L, Nalbant P. (2022)
Monitoring the Response of Multiple Signal Network Components to Acute Chemo-Optogenetic Perturbations in Living Cells.
Chembiochem. 23:e202100582

Kamps D, Koch J, Juma VO, Campillo-Funollet E, Graessl M, Banerjee S, Mazel T, Chen X, Wu YW, Portet S, Madzvamuse A, Nalbant P, Dehmelt L, (2020).
Optogenetic Tuning Reveals Rho Amplification-Dependent Dynamics of a Cell Contraction Signal Network.
Cell Reports 33(9):108467

Chen X, Venkatachalapathy M, Dehmelt L, Wu Y-W:
Multi-directional activity control (MAC) of cellular processes enabled by a versatile chemo-optogenetic approach.
Angew Chem Int Ed, 57:11993 (2018) (impact factor 11.26)

Nalbant P, Dehmelt L:
Exploratory cell shape changes: a sense of touch for cells?
Biol Chem (2018) 399:809 (corresponding author) (impact factor 3.27)

Graessl M, Koch J, Calderon A, Kamps D, Banerjee S, Mazel T, Schulze N, Jungkurth JK, Patwardhan R, Solouk D, Hampe N, Hoffmann B, Dehmelt L, Nalbant P:
An excitable Rho GTPase signaling network generates dynamic subcellular contraction patterns,
J Cell Biol. 216:4271 (2017) (featured in Spotlight article J Cell Biol. 216: 3899; corresponding author) (impact factor 7.96)

Kamps D, Dehmelt L.
Deblurring Signal Network Dynamics.
ACS Chem Biol. 12:2231 (2017) (corresponding author) (impact factor 5.00)

Chen X, Venkatachalapathy M, Kamps D, Weigel S, Kumar R, Orlich M, Garrecht R, Hirtz M, Niemeyer CM, Wu Y-W, Dehmelt L,
Molecular Activity Painting”: Switch-like, Light-Controlled Perturbations inside Living Cells,
Angew Chem Int Ed 56:5916 (2017) (corresponding author) (impact factor 11.26)

Arndt HD, Rizzo S, Nöcker C, Wakchaure VN, Milroy LG, Bieker V, Calderon A, Tran TT, Brand S, Dehmelt L, Waldmann H:
Divergent solid-phase synthesis of natural product-inspired bipartite cyclodepsipeptides: total synthesis of seragamide A.
Chemistry 21:5311 (2015) (impact factor 5.73)

Liu P, Calderon A, Konstantinidis G, Hou J, Voss S, Chen X, Li F, Banerjee S, Hoffmann J-E, Theiss C, Dehmelt L, Wu Y-W:
A Bioorthogonal Small-molecule Switch System for Controlling Protein Function in Cells.
Angew Chem Int Ed 53:10049 (2014) (impact factor 11.26)

Dehmelt L:
Cytoskeletal self-organization in neuromorphogenesis.
Bioarchitecture 4:75 (2014) (corresponding author) (impact factor N/A)

Arrabito G, Schroeder H, Schröder K, Filips C, Marggraf U, Dopp C, Venkatachalapathy M, Dehmelt L, Bastiaens PIE, Neyer A, and Niemeyer CM:
Configurable Low-cost Plotter Device for Fabrication of Multi-Color Sub-Cellular Scale Microarrays.
Small 10:2870 (2014) (impact factor 8.37)

Schulze N, Gräßl M, Soares AB, Geyer M, Dehmelt L, Nalbant P:
FHOD1 regulates stress fiber organization by controlling transversal arc and dorsal fiber dynamics.
J Cell Sci 127:1379 (2014) (impact factor 5.43)

Mazel T, Biesemann A, Krejczy M, Nowald J, Müller O and Dehmelt L:
Direct observation of microtubule pushing by cortical dynein in living cells.
Mol Biol Cell 25:95 (2014) (corresponding author) (impact factor 4.47)

Arens J, Duong T-T and Dehmelt L:
A Morphometric Screen Identifies Specific Roles for Microtubule-Regulating Genes in Neuronal Development of P19 Stem Cells.
PLoS One 8:e79796 (2013) (corresponding author) (impact factor 3.23)

Arrabito G, Reisewitz S, Dehmelt L, Bastiaens PI, Pignataro B, Schroeder H, and Niemeyer CM:
Biochips for Cell Biology by Combined Dip-Pen Nanolithography and DNA-Directed Protein Immobilization.
Small 9:4243 (2013) (impact factor 8.37)

Schönichen A, Mannherz HG, Behrmann E, Mazur AJ, Kühn S, Fackler OT, Raunser S, Dehmelt L and Geyer M:
FHOD1 is an actin bundling factor that dynamically and selectively associates with stress fibers and actin arcs.
J Cell Sci 126:1891 (2013) (impact factor 5.43)

Gandor S, Reisewitz S, Venkatachalapathy M, Arrabito G, Reibner M, Schröder H, Ruf K, Niemeyer CM, Bastiaens PIH, Dehmelt L:
A Protein Interaction Array Inside a Living Cell.
Angew Chem Int Ed 52:4790 (2013) (featured in Faculty of 1000 and Biotechniques 2013 55:11; corresponding author) (impact factor 11.26)
Blümer J, Rey J, Dehmelt L, Mazel T, Bastiaens P, Goody RS, Itzen A:
RabGEFs are sufficient for specific Rab membrane targeting.
J Cell Biol 200:287 (2013) (featured in Faculty of 1000) (impact factor 9.83)

Tennstaedt A, Pöpsel S, Truebestein L, Hauske P, Brockmann A, Schmidt N, Irle I, Sacca B, Niemeyer CM, Brandt R, Ksiezak-Reding H, Tirniceriu AL, Egensperger R, Baldi A, Dehmelt L, Kaiser M, Huber R, Clausen T, Ehrmann M:
Human high temperature requirement serine protease A1 (HTRA1) degrades tau protein aggregates.
J Biol Chem 287:20931 (2012) (impact factor 4.57)

Milroy LG, Rizzo S, Calderon A, Ellinger B, Erdmann S, Mondry J, Verveer P, Bastiaens P, Waldmann H, Dehmelt L, Arndt HD:
Selective chemical imaging of static actin in live cells.
J Am Chem Soc 134:8480 (2012) (corresponding author) (impact factor 12.11)

Dehmelt L, Poplawski G, Hwang E, Halpain S: NeuriteQuant:
An open source toolkit for high content screens of neuronal morphogenesis.
BMC Neurosci 12:100 (2011) (corresponding author) (impact factor 2.67)

Dehmelt L:
The dynamics of the cellular skeleton. How molecular "speckles" can reveal cellular building blocks.
Systembiologie.De (Int. Ed.) 3:59 (2011) (corresponding author) (impact factor N/A)

Dehmelt L and Bastiaens P
Self-Organization in Cells.
In Principles of Evolution (eds. H. Meyer-Ortmanns and S. Thurner), pp. 219-238. Heidelberg: Springer. (2011) (impact factor N/A)

Fath T, Fischer RS, Dehmelt L, Halpain S, Fowler VM:
Tropomodulins are negative regulators of neurite outgrowth.
Eur J Cell Biol 90:291 (2011) (impact factor 3.83)

Dehmelt L and Bastiaens PI:
Spatial organization of intracellular communication: insights from imaging.
Nat Rev Mol Cell Biol 11:440 (2010) (impact factor 37.81)

Weinrich D, Köhn M, Jonkheijm P, Westerlind U, Dehmelt L, Engelkamp H, Christianen PC, Kuhlmann J, Maan JC, Nüsse D, Schröder H, Wacker R, Voges E, Breinbauer R, Kunz H, Niemeyer CM, Waldmann H.
Preparation of biomolecule microstructures and microarrays by thiol-ene photoimmobilization.
Chembiochem 11:235 (2010) (impact factor 3.09)

Halpain S, Calabrese B, and Dehmelt L:
Actin Cytoskeleton in Growth Cones, Nerve Terminals, and Dendritic Spines.
Encyclopedia for Neuroscience, (Ed. Larry Squire), pp. 15-21. (2008) (impact factor N/A)

Dehmelt L, Halpain S.:
Neurite Outgrowth: A Flick of the Wrist.
Curr Biol 17:R611 (2007) (impact factor 9.57)

Dehmelt L, Nalbant P, Steffen W, Halpain S.:
A Microtubule-Based, Dynein-Dependent Force Induces Local Cell Protrusions: Implications for Neurite Initiation.
Brain Cell Biology 35:39 (2006) (impact factor 3.25)

Halpain S, Dehmelt L:
The MAP1 family of microtubule-associated proteins.
Genome Biology 7:224 (2006) (corresponding author) (impact factor 10.81)

Dehmelt L, Halpain S:
MAP2/tau family proteins.
Genome Biology 6:204 (2005) (impact factor 10.81)

Roger B, Al-Bassam J, Dehmelt L, Milligan RA, Halpain S:
MAP2c, but not tau, binds and bundles F-actin via its microtubule binding domain.
Curr Biol 14:363 (2004) (featured in N&V, Nature Cell Biology 6:390) (impact factor 9.57)

Dehmelt L, Halpain S:
Actin and microtubules in neurite initiation: Are MAPs the missing link?
J Neurobiol 58:18 (2004) (impact factor 3.84)

Dehmelt L, Smart FM, Ozer RS, Halpain S:
The role of microtubule-associated protein 2c in the reorganization of microtubules and lamellipodia during neurite initiation.
J Neurosci 23:9479 (2003) (impact factor 6.34)

Werner A, Preston-Fayers K, Dehmelt L, Nalbant P:
Regulation of the NPT gene by a naturally occurring antisense transcript.
Cell Biochem Biophys 36:241 (2002) (impact factor 1.68)

Lerche C, Seebohm G, Wagner CI, Scherer CR, Dehmelt L, Abitbol I, Gerlach U, Brendel J, Attali B, Busch AE:
Molecular impact of MinK on the enantiospecific block of IKs by chromanols.
Br J Pharmacol 131:1503 (2000) (impact factor 4.84)

Nalbant P, Boehmer C, Dehmelt L, Wehner F, Werner A:
Functional characterization of a Na+-phosphate cotransporter (NaPi-II) from zebrafish and identification of related transcripts.
J Physiol 520:79 (1999) (impact factor 5.04)

Werner A, Dehmelt L, Nalbant P:
Na+-dependent phosphate cotransporters: The NaPi protein families.
J Exp Biol 201:3135 (1998) (impact factor 2.90)