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Center for Mass Spectrometry

Dr. Sebastian Zühlke – Head of Laboratory Foto von Dr. Sebastian Zühlke

Telefon
(+49)231 755-4088

Adresse

Technische Universität Dortmund
Fakultät für Chemie und Chemische Biologie / GE
Otto-Hahn-Straße 6
44227 Dortmund
Deutschland

Campus Adresse
Campus Nord
Chemiegebäude

Raum C2-06-530

Veröffentlichungen

2020

Veröffentlichungen

  1. Daoud, F.; Zühlke, S.; Spiteller, M.; Kayser, O. (2020).
    Ozonation of rivaroxaban production waste water and comparison of generated transformation products with known in vivo and in vitro metabolites.
    Science of the Total Environment, 714, 136825.
    Weitere Informationen ...

2019

Veröffentlichungen

  1. Winkelmann, T; Smalla, K; Amelung, W; Baab, G; Grunewaldt-Stöcker, G; Kanfra, X; Meyhöfer, R; Reim, S; Schmitz, M; Vetterlein, D; Wrede, A; Zühlke, S.; Grunewaldt, J; Weiß, S; Schloter, M. (2019).
    Apple Replant Disease: Causes and Mitigation Strategies.
    Current Issues in Molecular Biology, 30, 89-105.
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2018

Veröffentlichungen

  1. Sezgin, S.; Hassan, R.; Zühlke, S.; Kuepfer, L.; Hengstler, J.G.; Spiteller, M.; Ghallab, A. (2018).
    Spatio-temporal visualization of the distribution of acetaminophen as well as its metabolites and adducts in mouse livers by MALDI MSI.
    Archives of Toxicology, 92, 2963-2977.
    Weitere Informationen ...

  2. Happi, G.M.; Talontsi, F.M.; Laatsch, H.; Zühlke, S.; Ngadjui, B.T.; Spiteller, M.; Kouam, S.F. (2018).
    seco-Tiaminic acids B and C: Identification of two novel 3,4-seco-tirucallane triterpenoids isolated from the root of Entandrophragma congoense (Meliaceae).
    Fitoterapia, 124, 17-22.
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2017

Veröffentlichungen

  1. Daoud, F.; Pelzer, D.; Zühlke, S.; Spiteller, M.; Kayser, O. (2017).
    Ozone pretreatment of process waste water generated in course of fluoroquinolone production
    Chemosphere, 185, 953-963.
    Weitere Informationen ...

2016

Veröffentlichungen

  1. Kusari, S.; Tatsimo, S. J. N.; Zühlke, S.; Spiteller, M. (2016).
    Synthetic origin of tramadol in the environment. Angewandte Chemie International Edition, 55, 240-243;
    Angewandte Chemie, 128, 248-251.
    Weitere Informationen ...

  2. Hannappel, S.; Koepp, C.; Zühlke, S.; Balzer, F.; Schulz, D. (2016).
    Identification of antibiotic input sources into groundwater under areas with high livestock densities
    Grundwasser, 21 (4), 295-304.
    Weitere Informationen ...

  3. Balzer, F.; Zühlke, S.; Hannappel, S. (2016).
    Antibiotics in groundwater under locations with high livestock density in Germany
    Water Science and Technology-Water Supply 16 (5), 1361-1369.
    Weitere Informationen …

  4. Kusari, P.; Kusari, S.; Eckelmann, D.; Zühlke, S.; Kayser, O.; Spiteller, M. (2016).
    Cross-species biosynthesis of maytansine in Maytenus serrata.
    RSC Advances, 6, 10011-10016.
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  5. Kyekyeku, J. O.; Kusari, S.; Adosraku, R. K.; Zühlke, S.; Spiteller, M. (2016).
    Prenylated 2-arylbenzofuran derivatives with potent antioxidant properties from Chlorophora regia (Moraceae).
    Fitoterapia, 108, 41-47.
    Weitere Informationen …

  6. Kusari, P.; Kusari, S.; Eckelmann, D.; Zühlke, S.; Kayser, O.; Spiteller, M. (2016):
    Cross- species biosynthesis of maytansine in Maytenus serrata
    RSC Advances, 6, 10011-10016.
    Weitere Informationen ...

  7. Kusari, S.; Tatsimo, S. J. N.; Zühlke, S.; Spiteller, M. (2016):
    "Synthetic origin of tramadol in the environment" Angewandte Chemie International Edition, 55, 240-243; Hot Paper; featured on Back Cover. [Angewandte Chemie 2016, 128, 248-251].
    Weitere Informationen ...

  8. Oppong Kyekyeku, J.; Kusari, S.; Adosraku, R. K.; Zühlke, S.; Spiteller, M. (2016):
    "Prenylated 2- arylbenzofuran derivatives with potent antioxidant properties from Chlorophora regia (Moraceae)"
    Fitoterapia, 108, 41-47.
    Weitere Informationen ...


Poster

  1. Eckelmann, D.; Kusari, S.; Kusari, P.; Zühlke, S.; Kayser, O.; Spiteller, M. (2016):
    "Investigation of maytansine biosynthesis in Maytenus serrata and identification of precursors by HPLC- HRMSn. At the 9th Tag der Chemie (Chemistry Day), Department of Chemistry and Chemical Biology, TU Dortmund, Germany; dated 19 February 2016".

  2. Kusari, S.; Kusari, P.; Eckelmann, D.; Zühlke, S.; Kayser, O.; Spiteller, M. (2016):
    "Cross- species biosynthesis of maytansine in Maytenus serrata plants", At the 28. Irseer Naturstofftage; venue: Schwäbisches Tagungs- und Bildungszentrum Kloster Irsee; dated: 24- 26th Feb 2016.

2015

Veröffentlichungen

  1. Happi, G.M., Kouam , S.F., Talontsi, M.F., Zühlke, S., Lamshöft, M., Spiteller, M. (2015):
    "Minor secondary metabolites from the bark of Entandrophragma congoënse (Meliaceae" Fitoterapia, 102, 35-40.

  2. Reetz, J.; Schulz, W.; Seitz, W.; Spiteller, M.; Zühlke, S.; armbruster, W.; wallner, K. (2015):
    "Uptake of Neonicotinoid Insecticides by Water- Foraging Honey Bees (Hymenoptera: Apidae) Through Guttation Fluid of Winter Oilseed Rape" Journal of Economic Entomology.
    Weitere Informationen …

  3. Rudolph-Mohr, N.; Gottfried, S.; Lamshöft, M.; Zühlke, S.; Oswald, S.E.; Spiteller, M. (2015):
    "Non- invasive imaging techniques to study O2 micro- patterns around pesticide treated lupine roots" Geoderma, 239-240, 257-264.


Vorträge:

  1. Kusari, S.; Lamshöft, M.; Kusari, P.; Gottfried, S.; Zühlke, S.; Hentschel, U.; Kayser, O.; Spiteller, M. (2015):
    "Hiding in plain sight, root endophytic community is the ‘true’ producer of maytansine in Putterlickia plants", At the Annual Conference of the Association for General and Applied Microbiology [Jahrestagung der Vereinigung für Allgemeine und Angewandte Mikrobiologie (VAAM)]; venue: Marburg, Germany; dated: 01–04 March 2015.

  2. Spiteller, M.; Kusari, S.; Tatsimo, S. J. N.; Zühlke, S. (2015):
    "Stable isotope analysis and 14C- AMS confirming synthetic origin of tramadol in environmental samples", At the International Isotope Society- Central European Division(IIS- CED) Workshop, Bad Soden, Germany; dated 1- 2 October 2015.

  3. Zühlke, S.; Hannappel, S.; Balzer, F. (2015):
    "Findings of Antibiotics in Groundwater Under Worst Case Criteria in the Agricultural Environment in Germany" 15th EuCheMS International Conference on Chemistry and the Environment, 20 - 24 September, ICCE2015.
    download PDF (11,2 kB)

2014

Veröffentlichungen

  1. Kusari, S.; Tatsimo, S. J. N.; Zühlke, S.; Talontsi, F. M.; Kouam, S. F.; Spiteller, M. (2014):
    "Tramadol – a true natural product?" Angewandte Chemie International Edition, 53, 12073-12272; VIP - Very Important Paper. [Angewandte Chemie 126, 12269-12272].
    Weitere Informationen ...

  2. Choi, J.-H.; Lamshöft, M.; Zühlke, S.; Abd El-aty, AM.; Rahman, MM.; Kim, SW.; Shim, JH.; Spiteller, M.; (2014):
    "Analyses and decreasing patterns of veterinary antianxiety medications in soils" JOURNAL OF HAZARDOUS MATERIALS, 275, 154-165.

  3. Choi, J.-H.; Lamshöft, M.; Zühlke, S.; Park, JH.; Rahman, MM.; Abd El-Aty, AM.; Spiteller, M.; Shim, JH. (2014):
    "Determination of anxiolytic veterinary drugs from biological fertilizer blood meal using liquid chromatography high- resolution mass spectrometry" Biomedical Chromatography, 28 (6), 751-759.

  4. Dealtry, S., Holmsgaard, PN., Dunon, V., Jechalke, S., Ding, GC., Krogerrecklenfort, E., Heuer, H., Hansen, LH., Sprringael, D., Zühlke, S., Sorensen, SJ., Smalla, K. (2014):
    "Shifts in Abundance and Diversity of Mobile Genetic Elements after the Introduction of Diverse Pesticides into an On- Farm Biopurification System over the Course of a Year" APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 80 (13), 4012-4020.

  5. Hannappel, S., Balzer, F., Groeneweg, J., Zühlke, S., Schulz, d. (2014):
    "Incidence of veterinary drugs in near- surface groundwater below sites with high livestock density in Germany" HYDROLOGIE UND WASSERBEWIRTSCHAFTUNG, 58, 208-220.

  6. Kusari, S.; Lamshöft, M.; Kusari, P.; Gottfried, S.; Zühlke, S.; Louven, K.; Hentschel, U.; Kayser, O.; Spiteller, M. (2014):
    "Endophytes are hidden producers of maytansine in Putterlickia roots" Journal of Natural Products, 77, 2577-2584 (ACS Editors Choice article; C&EN magazine-Dec 2014 edition; 2014 Arthur E. Schwarting Award from American Society of Pharmacognosy/ Journal of Natural Products).
    Weitere Informationen ...

2013

Veröffentlichungen

  1. Ratsak, C.; Guhl, B.; Zühlke, S.; Delschen, T. (2013):
    "Veterinarantibiotikaruckstande in Gulle und Garresten aus Nordrhein- Westfalen" Environmental Science Europe, 25:7, in press.

  2. Sukul, P.; Lamshöft, M.; Zühlke, S.; Spiteller, M. (2013):
    "Evaluation of sorption- desorption processes for metalaxyl in natural and artificial soils" Journal of Environmental Science and Health, Part B, 48(6), 431-441.

  3. Sulimma, L.; Bullach, A.; Kusari, S.; Lamshöft, M.; Zühlke, S.; Spiteller, M. (2013):
    "Enantioselective degradation of the chiral fungicides Metalaxyl and Furalaxyl by Brevibacillus brevis" Chirality, 25(6), 336-340.


Poster

  1. Goebbels, E.; Oerke, E.-C.; Zühlke, S.; Dehne, H.-W. (2013):"Influence of timing on the effect of azole fungicides on Fusarium infection of wheat varieties differing in susceptibility" 17. Internationale Reinhardsbrunn Symposium, Friedrichsroda, 21.4.-25.4.2013 .